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KMID : 0355420090330030339
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Journal of Korean Academy of Oral Health
2009 Volume.33 No. 3 p.339 ~ p.345
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Effect of water-soluble reduced chitosan on volatile sulfur compounds
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Bae Kwang-Hak
Ha Jung-Eun
Jun Eun-Joo
Han Dong-Hun
Paik Dai-Il
Kim Jin-Bom
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Abstract
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Objectives: This study examined the effects of newly developed water-soluble reduced chitosan on the volatile sulfur compounds induced by 4-day plaque regrowth.
Methods: 1.0% water-soluble reduced chitosan with a pH ranging from 6.0 to 6.5, a molecular weight between 3,000 and 5,000 Da, and a 70% of degree of deacetylation was used. The amounts of volatile sulfur compounds in the mouth air were measured in vivo. Twelve dental students volunteered to participate in this double blind, randomized, 4-day plaque regrowth study. The subjects were divided into three groups and asked to rinse with the allocated mouthrinse solution and refraining from all mechanical oral hygiene measures.
Results: The chitosan mouthwash reduced significantly the amounts of hydrogen sulfide in the mouth air compared to DW.
Conclusions: The water-soluble reduced chitosan exhibited significant malodor-reducing activity during the 4-day plaque regrowth experiment.
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KEYWORD
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oral malodor, volatile sulfur compounds, water-soluble reduced chitosan
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